Zlecenie 7751216 - Nowe, małocząsteczkowe leki immunomodulujące w terapii...

he live cell format* Mass spec based approach for comprehensively profiling native kinases in cell or tissue lysates. Based on a desthiobiotin ATP (or ADP) acyl phosphate probe to covalently modify kinases in the active site. Provides the ability to broadly and quantitatively profile native protein and lipid kinases in cell or tissue lysates, without the need for recombinant protein expression or substrate-based assay development. Possible to use to test selectivity of compounds on human PBMC in the live cell format. Option 1) 2 compounds, 2 dozes Option 2) 4 compounds, 1 dose * - the Ordering Party reserves the right to change lysate/live cell format and test on selected cell line/ primary cells 1. offer validity period – at least till 31st December 2020. 2. Turnaround time – max. 4 weeks.